Early on, Irina Muresanu has acquired international acclaim as an outstanding young soloist, recitalist and chamber musician having achieved top prizes in numerous international violin competitions. These include the Montreal International, UNISA International String, Washington International, and the Schadt String Competitions. She is also the winner of the Pro Musicis International Award, the Presser Music Award and the Arthur Foote Award from the Harvard Musical Association and the Paul Rolland Award.

Irina Muresanu has performed in renowned concert halls throughout North America, Europe and Asia. Her recent engagements as a soloist include concerts with the Boston Pops, the Orchestre de la Suisse Romande (Geneva), the Syracuse Symphony, the Metropolitan Orchestra (Montreal), the Transvaal Philharmonic (Pretoria), the Orchestre de la Radio Flamande (Brussels), the Boston Phiharmonic, the Willliamsburg Sinfonia, the Pro Arte Chamber Orchestra, the Romanian National Radio Orchestra, the New England String Ensemble and the Miami Symphony Orchestra among others. The Civic Symphony of Boston commissioned a violin concerto from composer Thomas Oboe Lee to be written especially for Irina Muresanu, which she premiered in 2010.

In 2008, Irina Muresanu (along with pianist Michael Lewin) released the integrale of William Bolcom's violin and piano sonatas for the Centaur label, funded by a Copland Recording Grant award. In Europe, her recording of the Guillaume Lekeu and Alberic Magnard late Romantic violin and piano sonatas (with pianist Dana Ciocarlie) for the AR RE-SE French label has sparked enthusiasm. She has also recorded the world premiere recording of Marion Bauer's Sonata for Violin and Piano (with pianist Virginia Eskin) on Albany Records, a CD with chamber works of Andy Vores, and a CD featuring chamber works of Erich Korngold released by the VPRO Radio Amsterdam. Adding to her other competition laurels, Irina Muresanu has been granted a Special Commendation award for her recording of Schoenberg's Fantasy for violin and piano at the 3rd International Vienna Modern Masters Performers Recording Competition.

Irina Muresanu’s talents have been sought out for collaboration with such noted performers as Kim Kashkashian, Cynthia Phelps, Sharon Robinson, Ronald Thomas, Andres Cardenes, Ilya Kaler, and Nathaniel Rosen. An active chamber musician, she has appeared in such festivals and venues as Bargemusic in New York; the Rockport Festival in Massachusetts; Bay Chambers concert series and Bowdoin Festival in Maine; the Strings in the Mountains and San Juan Music festival in Colorado; Maui Chamber Music Festival in Hawaii, Reizend Music festival in Netherlands; Festival van de Leie in Belgium; and the Renncontres des Musiciennes festival in France. She has been a member of the Boston Trio since 2002 and she performs with the Andover Chamber Music Society, the Walden Chamber Players and the Boston Chamber Music Society.

Irina Muresanu currently serves on both the faculties of the Boston Conservatory and the Music Department at Harvard University. She was appointed Artist-in-Residence as a member of the Lewin-Muresanu Duo at the Boston Conservatory and her ensemble, the Boston Trio, is Ensmble-in-Residence at the New England Conservatory. A native of Bucharest, Romania, she received the prestigious Artist Diploma (1999) and a Doctorate in Musical Arts degree (2009) from the New England Consevatory.

She plays a 1856 Giuseppe Rocca violin and a Charles Peccat bow courtesy of Mr. Mark Ptashne.